DDE prioritization summary

Compiled are abstracts from developmental and reproductive epidemiologic and animal toxicity studies and other relevant investigations. This information was used in a screen to select appropriate chemicals for presentation to the Developmental and Reproductive Toxicant Identification Committee as possible candidates for Committee consideration. The criterion for passing this screen is the existence of two or more analytical epidemiologic studies judged to be of adequate quality that reported increased risk of adverse developmental or reproductive outcomes. The epidemiologic studies report on developmental and reproductive sequelae related to environmental exposures to DDE. Since blood levels of DDE will result from environmental exposures to DDE, all study abstracts that reported serum levels of DDE are considered to be relevant to environmental exposures to DDE, even if in some cases the environmental exposure may have been to DDT or a mixture of DDT and DDE. Based on a review of abstracts of the following studies, the chemical passed the epidemiologic screen.