Corrections to Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography
نویسندگان
چکیده
Corrections to Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography [J. Med. Chem. 2009, 52, 4694. DOI: 10.1021/jm900259h]. Douglas R. Davies, Bjorn Mamat, Olafur T. Magnusson, Jeff Christensen, Magnus H. Haraldsson, Rama Mishra, Brian Pease, Erik Hansen, Jasbir Singh, David Zembower, HidongKim,AlexS.Kiselyov,AlexB.Burgin,MarkE.Gurney, and Lance J. Stewart*
منابع مشابه
Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography†
We describe a novel fragment library termed fragments of life (FOL) for structure-based drug discovery. The FOL library includes natural small molecules of life, derivatives thereof, and biaryl protein architecture mimetics. The choice of fragments facilitates the interrogation of protein active sites, allosteric binding sites, and protein-protein interaction surfaces for fragment binding. We s...
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