Thermally switchable polymers achieve controlled Escherichia coli detachment.

A Self-Switchable Polymer Reactor for Controlled Catalytic Chemistry Processes with a Hyperbranched Structure

A self-switchable polymer reactor with a hyperbranched structure for controlled catalytic chemistry processes is reported. This polymer reactor was made of silver nanoparticles and a polymer carrier consisting of hyperbranched polyethylenimine and hydroxyethyl acrylate that behaved as thermally switchable domains. Below the transfer temperature, relatively strong catalytic reactivity was demons...

Nanopatterned antimicrobial enzymatic surfaces combining biocidal and fouling release properties.

Surfaces incorporating the antimicrobial enzyme, lysozyme, have been previously demonstrated to effectively disrupt bacterial cellular envelopes. As with any surface active antimicrobial, however, lysozyme-expressing surfaces become limited in their utility by the accumulation of dead bacteria and debris. Surfaces modified with environmentally responsive polymers, on the other hand, have been s...

Nanopatterned polymer brushes as switchable bioactive interfaces.

We report convenient methods for synthesis of nanopatterned, thermally responsive brushes of poly(N-isopropyl acrylamide) over large areas (e.g., 1 cm(2)) to form model, dynamic, biofunctional surfaces. The new nanopatterned brush structure can be used to control (i) the rate of both nonspecific and biospecific adsorption processes at the polymer-graft-free regions of the substrate, and (ii) th...

Fed-batch Cultivation of Recombinant Escherichia coli Producing Human Interferon-γ Under Controlled Specific Growth Rate

Synthesis of novel biodegradable antibacterial grafted xanthan gum.

Xanthan gum (XG) is natural polysaccharides used in food industries as stabilizers and thickener agents. The problem is that some food products are found to be contaminated by pathogenic bacteria such as Escherichia coli (E. coli) and Staphyloccus aureus (S. aureus) that reduce their shelf life. This research aims to synthesize biodegradable antibacterial XG-grafted-poly(N-vinyl imidazole) PVI ...