FLASH: a rapid method for prototyping paper-based microfluidic devices.

نویسندگان

  • Andres W Martinez
  • Scott T Phillips
  • Benjamin J Wiley
  • Malancha Gupta
  • George M Whitesides
چکیده

This article describes FLASH (Fast Lithographic Activation of Sheets), a rapid method for laboratory prototyping of microfluidic devices in paper. Paper-based microfluidic devices are emerging as a new technology for applications in diagnostics for the developing world, where low cost and simplicity are essential. FLASH is based on photolithography, but requires only a UV lamp and a hotplate; no clean-room or special facilities are required (FLASH patterning can even be performed in sunlight if a UV lamp and hotplate are unavailable). The method provides channels in paper with dimensions as small as 200 microm in width and 70 microm in height; the height is defined by the thickness of the paper. Photomasks for patterning paper-based microfluidic devices can be printed using an ink-jet printer or photocopier, or drawn by hand using a waterproof black pen. FLASH provides a straightforward method for prototyping paper-based microfluidic devices in regions where the technological support for conventional photolithography is not available.

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عنوان ژورنال:
  • Lab on a chip

دوره 8 12  شماره 

صفحات  -

تاریخ انتشار 2008