Biological motors: Energy storage in myosin molecules
نویسنده
چکیده
A recent experiment of exceptional complexity has shown that a myosin may lose its ATP but store the energy from it and attach to actin and perform a working stroke several hundred milliseconds later.
منابع مشابه
Duty ratio of cooperative molecular motors
Motor proteins are specialized molecules that convert chemical energy into useful mechanical work and govern many important biological processes. They bind to actin filaments and microtubules and use them as tracks, on which they propagate in order to transport different types of cargo across the cell. Among these molecules we find myosin II motors that interact with elastic actin filaments. My...
متن کاملCytoskeleton Molecular Motors: Structures and Their Functions in Neuron
Cells make use of molecular motors to transport small molecules, macromolecules and cellular organelles to target region to execute biological functions, which is utmost important for polarized cells, such as neurons. In particular, cytoskeleton motors play fundamental roles in neuron polarization, extension, shape and neurotransmission. Cytoskeleton motors comprise of myosin, kinesin and cytop...
متن کاملStructural and Functional Insights on the Myosin Superfamily
The myosin superfamily is a versatile group of molecular motors involved in the transport of specific biomolecules, vesicles and organelles in eukaryotic cells. The processivity of myosins along an actin filament and transport of intracellular 'cargo' are achieved by generating physical force from chemical energy of ATP followed by appropriate conformational changes. The typical myosin has a he...
متن کاملThe way things move: looking under the hood of molecular motor proteins.
The microtubule-based kinesin motors and actin-based myosin motors generate motions associated with intracellular trafficking, cell division, and muscle contraction. Early studies suggested that these molecular motors work by very different mechanisms. Recently, however, it has become clear that kinesin and myosin share a common core structure and convert energy from adenosine triphosphate into...
متن کاملRealistic Models of Biological Motion
The origin of biological motion can be traced back to the function of molecular motor proteins. Cytoplasmic dynein and kinesin transport organelles within our cells moving along a polymeric filament, the microtubule. The motion of the myosin molecules along the actin filaments is responsible for the contraction of our muscles. Recent experiments have been able to reveal some important features ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Current Biology
دوره 8 شماره
صفحات -
تاریخ انتشار 1998