Genetic Differences and Human Identities

نویسندگان

  • Yvonne Melia
  • Paul Pharoah
  • Martin Richards
چکیده

T his report is one product of a large project un-dertaken by The Hastings Center and the Amer-ican Association for the Advancement of Science and funded by the Ethical, Legal, and Social Implications division of the National Human Genome Research Institute. Mark Frankel and Audrey Chap-man (from AAAS) and I worked from the very beginning to develop the project and submit the grant application to NHGRI. From The Hastings Center, Erika Blacksher, Mark Hanson, and Ashby Sharpe also participated in these early discussions. We could not have completed the grant application, much less the project, without the tireless, erudite, and wise advice of V. Elving Anderson, professor emeritus of genetics at the University of Minnesota. All of us who participated in this project owe Elving a great debt of gratitude. Once the grant was under way, Audrey, Mark, Elv-ing and I were joined by Catherine Baker and Nancy Press to form a steering committee that shared the responsibility for making all of the decisions relevant to the project, from setting meeting agendas to identifying background readings, holding a public meeting in Washington, D.C., and creating a primer of be-havioral genetics, a book of essays, and this report. Working with Nancy, Cathy, Audrey, Mark, and Elving was a pleasure and an honor. The steering committee was part of a larger working group, whose members are listed on the facing page. On some topics, additional help was provided by consultants: We were joined at one of our working group meetings by members of the United Kingdom's Nuffield Council, which has explored similar questions: Administering such a complicated grant isn't always easy. My colleagues and I are deeply grateful to Joy Boyer at the ELSI office for her always thoughtful, kind, and patient support of our work. Over the years of the project we benefited from the logistical support of Kevin Alleman, Rachel Gray, and Sharon Leu at AAAS and from the research assistance of Hasbrouck at the Center, whose work made our project meetings both productive and pleasant. Thanks to Jaime Bishop and Eric Trump for their work in the office of the Hastings Center Report. Thanks also to the Report's art director, Nora Porter, for carefully reading and then creatively presenting this report. Gregory Kaebnick, editor of the Report, edited this special supplement not only for style, but also for content. It is wonderful to work with such a talented philosopher …

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

First Report of a set of Genetic Identities in Prunus Rootstocks by SSR Markers

Prunus rootstocks play an important role in modern horticulture and commercial orchards owing to their responsibility for a wide range of characters from compatibility with cultivars to adaptation to biotic and abiotic stresses. In this study, Thirty Prunus rootstock samples were tested by 25 microsatellite markers in order to identify the genetic identity and relationships among them.17 SSR ma...

متن کامل

Human Microbiome

Humans are almost identical in their genetic pattern, but the slight differences in our DNA lead to remarkable phenotypic variation among the human population. There are a variety of microbial communities and their genes (microbiomes) in the human body that play an essential role in human health and disease. The microbes inhabiting our bodies is quite a bit more variable, with only a third of i...

متن کامل

Genetic Variability of Antigen B8/1 among Echinococcus granulosus Isolates from Human, Cattle, and Sheep in Fars Province, Southern Iran

Background: Cystic echinococcosis (CE), known as hydatid cyst, is a zoonotic parasitic infection caused by the larval stage of Echinococcus granulosus (E. granulosus). Antigen B, the major component of hydatid cyst fluid, is encoded by members of a multigene family. The present study aimed to evaluate the genetic diversity of the gene encoding antigen B8/1 (EgAgB8/1) among the main intermediate...

متن کامل

Stem Cells Application in Modeling of Human Genetic Diseases

The use of animal models in modeling of human genetic disease has many advantages. In some cases, however, this method may not be applicable due to some limitations, such as differences in tissue composition, anatomy and physiology of humans and animals. Isogenic human disease models are a population of cells that are selected or engineered to model a specific genetic disease, in vitro. They ar...

متن کامل

Mitochondrial DNA variation, genetic structure and demographic history of Iranian populations

In order to survey the evolutionary history and impact of historical events on the genetic structure of Iranian people, the HV2 region of 141 mtDNA sequences related to six Iranian populations were analyzed. Slight and non-significant FST distances among the Central-western Persian speaking populations of Iran testify to the common origin of these populations from one proto-population. Mismatch...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2005