UPLC Analysis of Benzalkonium Chloride (BAC) in Consumer Products using ACQUITY UPLC CSH C18
نویسنده
چکیده
■ ■ 80% reduction in analysis time enables high throughput analysis IN T RODUC T ION Benzalkonium Chloride (BAC) refers to a series of quaternary ammonium chloride homologues with the structure shown in Figure 1. The pervasive use of BAC in consumer products results from its antiseptic and antifungal properties with widespread applications ranging from cleaning products and disinfectants to sanitizing wipes and ophthalmic solutions. Because of its extensive use, BAC has been the subject of numerous studies, including the evaluation of the reactivity of BAC with ocular tissue and the study of worldwide municipal wastewater, which found BAC to be the most prevalent quaternary ammonium compound in wastewater, with concentrations ranging between 200 and 300 mg/L.
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