High frequency electrical stimulation of the human skin induces heterotopical 1 mechanical hyperalgesia , heat hyperalgesia and enhanced responses to non - 2 nociceptive vibrotactile input
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چکیده
*Corresponding author: 12 Emanuel N van den Broeke 13 Institute of Neuroscience (IoNS) 14 Faculty of Medicine 15 Université catholique de Louvain 16 B-1200, Brussels 17 Belgium 18 E-mail: [email protected] 19 20 21 Running Head: HFS and hyperalgesia 22 23
منابع مشابه
High-frequency electrical stimulation of the human skin induces heterotopical mechanical hyperalgesia, heat hyperalgesia, and enhanced responses to nonnociceptive vibrotactile input.
High-frequency electrical stimulation (HFS) of the human skin induces increased pain sensitivity in the surrounding unconditioned skin. The aim of the present study was to characterize the relative contribution of the different types of nociceptive and nonnociceptive afferents to the heterotopical hyperalgesia induced by HFS. In 17 healthy volunteers (9 men and 8 women), we applied HFS to the v...
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*Corresponding author: 13 Emanuel N van den Broeke 14 Institute of Neuroscience (IoNS) 15 Faculty of Medicine 16 Université catholique de Louvain 17 B-1200, Brussels 18 Belgium 19 E-mail: [email protected] 20 21 22 Running Head: Secondary hyperalgesia and C fibers 23 24
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Long-term potentiation (LTP) and long-term depression (LTD) of synaptic strength are ubiquitous mechanisms of synaptic plasticity, but their functional relevance in humans remains obscure. Here we report that a long-term increase in perceived pain to electrical test stimuli was induced by high-frequency electrical stimulation (HFS) (5 x 1 sec at 100 Hz) of peptidergic cutaneous afferents (27% a...
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