Myosin II and dynamin control actin rings to mediate fission during activity-dependent bulk endocytosis.

of mouse lumbar spinal cord taken 7 d after partial sciatic nerve ligation. The section is stained for microglial markers Iba1 (red) and phosphorylated p-38 MAPK (green), as well as the nuclear marker DAPI (blue). The orphan G-protein receptor 84 (GPR84) is markedly induced in macrophages and microglia during inflammation, and it contributes to the development of mechanical and thermal hypersensitivity. For more information, see the article by Nicol et al. (pages 8959 – 8969). i This Week in The Journal