Comparison of two methods for calculating the frictional properties of articular cartilage using a simple pendulum and intact mouse knee joints.

Conditioned medium derived from mesenchymal Stem cells regenerates’ defected articular cartilage

Background & Aims: One of cell- based technical issues associated with cartilage repair assay is delivering cells to the site of the parts where damage is created. Mesenchymal stem cells (MSCs) with their chondrogenic potential are ideal candidates for cartilage regeneration. High expression of cartilage hypertrophy markers by MSCs would result in apoptosis and ossification. This investigation ...

Influence of the meniscus on friction and degradation of cartilage in the natural knee joint.

BACKGROUND Total meniscectomy has been shown to cause early-onset arthritis in the underlying cartilage and bone in the knee joint, demonstrating that the meniscus plays an important protective role in the load carrying capacity. Relationships between friction and wear in synovial joints are complex due to the biphasic nature of articular cartilage and the time dependency of tribological respon...

A Novel Method for Calculating the Frictional Properties of Articular Cartilage Using a Material Testing Machine

The Effect of Mesenchymal Stem Cells and Aqueous Extract of Elaeagnus Angustifolia on the Mechanical Properties of Articular Cartilage in an Experimental Model of Rat Osteoarthritis

Introduction: Although, the effect of direct intra-articular injection of bone marrow stem cells (BMSCs) on the repair of articular cartilage and the effect of Elaeagnus angustifolia extract on pain relief in patients with osteoarthritis have been investigated, no studies has been conducted to compare the effects of these two therapeutic methods on the mechanical properties of articular cartila...

Experimental Study on Protective Role of NSAID on Articular Cartilage Destruction in Septic Arthritis

Background: Surgical drainage and antibiotic therapy are the cornerstones of treatment protocols in septic arthritis; however, in some circumstances, the diagnosis and initiation of treatment may be retarded by slow disease progression or the time when the patient’s condition precludes early surgery. Therefore, it is beneficial to find ways to reduce the amount of articular injury. This study a...