Randomized Trial Study on Ramosetron and Dexamethasone in the Prevention of Nausea and Vomiting after Laparoscopic Cholecystectomy under General Anesthesia
نویسندگان
چکیده
objective: this study aims to identify whether dexamethasone can be used in the prevention of nausea and vomiting after laparoscopic cholecystectomy (LC) under general anesthesia. Methods: 400 patients who were performed with LC under general anesthesia were chosen and divided randomly into two groups with 200 patients each, namely ramosetron group and dexamethasone group. Results: there’s no significant difference in the effectiveness of complete inhibition of nausea and vomiting within 24 hours after the surgery in both groups (P> 0.050). Meanwhile, there’s no significant side effects in association with the anti-emetic drugs within 24 hours after the operation in both groups, either. Conclusion: Dexamethasone plays a similar effective role as Ramosetron in the prevention of nausea and vomiting after laparoscopic cholecystectomy under general anesthesia.
منابع مشابه
مقایسهی اثر دوز غیر هوشبر پروپوفول با دگزامتازون بر جلوگیری از تهوع و استفراغ بعد از عمل کله سیستکتومی لاپاراسکوپیک
Background and Objective: Post operative nausea and vomiting (PONV) are unpleasant feelings which frequently occur after laparoscopic cholecystectomy. The aim of this study was to compare the effectiveness of dexamethasone and propofol in prevention of PONV in patients undergoing laparoscopic cholecystectomy. Materials and Methods: 60 patients with ASA status 1-2, who had undergone laparoscopic...
متن کاملمقایسه اثر تجویز قبل از عمل اندانسترون ودگزامتازون در پیشگیری از تهوع و استفراغ بعد از کله سیستکتومی با لاپاراسکوپی
Background and purpose: Postoperative nausea and vomiting (PONV) is a side effect of anesthesia. Without prophylactic intervention, it occurs in about one-third of patients (10 to 60%) under general anesthesia. PONV could be more uncomfortable than postoperative pain. The aim of this study was to compare the efficacy of ondansetron and dexamethasone in reducing nausea and vomiting after laparos...
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BACKGROUND Selective 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists are reported to have potent antiemetic effects for postoperative nausea and vomiting (PONV). The purpose of this study was to prospectively evaluate the efficacy of palonosetron, granisetron, and ramosetron for the prevention of PONV in patients undergoing laparoscopic gynecologic surgery. METHODS In this prospective...
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