Are There Any Objections against Our Hypothesis That Buerger Disease Is an Infectious Disease?

نویسندگان

  • Takehisa Iwai
  • Makoto Umeda
  • Yoshinori Inoue
چکیده

In 1878, Winiwarter used a microscope and reported a case of 57 year-old man demonstrating Buerger disease. After that, 134 years passed. Leo Buerger and Edgar V. Allen strongly suggested that Buerger disease is an infectious disease without any doubt. Also, an etiologic point is the luminal infectious thrombus, which is thought to be the core of the disease. Many etiological factors were proposed and then discarded after academic scrutiny, but two big discoveries were made in 2005 and 2008. Namely, periodontal bacteria DNA was found in the occluded arteries of 93% of patients with Buerger disease, and periodontal bacteria (typical weak bacteria) were found to dwell in the platelets. Using these evidences, supported by genetic and epidemiological facts, we could almost explain the pathogenesis or clinical course of Buerger disease, which had been already studied.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Gluten - Not a Friendly Protein

Introduction: Gluten is a protein found in grains.  Research has shown that the gluten that is in grains of wheat, barley, rye, and oats (to a lesser degree) is toxic to many individuals.  While gluten is essential for the make-up of these 4 grains, our bodies do not need it. Is it healthful?  The protein in today’s wheat is poorly digested and can be harmful.  An estimated 95% of prepared fo...

متن کامل

Pathogenic Mechanism of the Artery and the Vein in Buerger Disease: Our Hypothesis

Our hypothesis started from the discovery of the periodontal bacteria DNA in occluded arteries and phlebitis veins of Buerger disease. It was accelerated by the observation of platelets and bacterial coexistence showing aggregation of platelets. Using our hypothesis, we would like to explain the characteristic points of Buerger disease that have already been reported in various documents. Our h...

متن کامل

An Interpretation of the Verses of the Prophet`s Wives (with an Emphasis on New Objections)

The holy Qur'an has not spared of any subject having to do with human guidance in the path of ascension and growth. Some opponents, however, have claimed some of the Quranic discourses as being unnecessary and ineffective in the field. As they claim, the discussion of these topics may be taken as a sign against originality of the Qur'an. Among these are the verses on the marriage of Prophet Muh...

متن کامل

The Spatial Allocation of Hospitals With Negative Pressure Isolation Rooms in Korea: Are We Prepared for New Outbreaks?

Background Allocation of adequate healthcare facilities is one of the most important factors that public health policy-makers consider when preparing for infectious disease outbreaks. Negative pressure isolation rooms (NPIRs) are one of the critical resources for control of infectious respiratory diseases, such as the novel coronavirus disease 2019 (COVID-19) outbreak. However, there is insuffi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Annals of vascular diseases

دوره 5 3  شماره 

صفحات  -

تاریخ انتشار 2012