The relationship between infection of human papilloma virus and risk of Chinese oral squamous cell carcinoma
نویسندگان
چکیده
Previous studies indicated that human papilloma virus (HPV) infection may be associated with risk of oral squamous cell carcinomas (OSCC). In this study, we evaluate the relationship OSCC and HPV infection in Chinese population via meta-analysis. A total of 7 articles were included in our study eligible case-control studies. After testing the heterogeneity of the studies by the Cochran Q test, the meta-analyses for HPV and HPV16 were performed using the random effects model. Quantitative meta-analyses showed that subjects OSCC with HPV infection increase 6.03 times risk of OSCC than subjects without HPV infection (OR=7.03, 95% CI: 3.88-12.76). High incidences of HPV infection may increase risk of OSCC In Chinese population.
منابع مشابه
The Prevalence of Human Papilloma Virus in Squamous Cell Carcinoma of Oral Tongue
Background and objective: Oral tongue Squamous Cell carcinoma (SCC) commonly involves males between the sixth to eighth decades of life. Major risk factors are tobacco usage and alcohol consumption. The increasing number of patients developing oral tongue cancer without these well-known risk factors suggests that a viral infection, such as Human Papil...
متن کاملThe Prevalence of Human Papilloma Virus in Esopha-geal Squamous Cell Carcinoma
Background: Carcinomas of esophagus, mostly squamous cell carcinomas, occur throughout the world. There are a number of suspected genetic or environmental etiologies. Human papilloma virus (HPV) is said to be a major etiology in areas with high incidence of esophageal carcinoma, while it is hardly detectable in low incidence regions. This study was designed to evaluate the prevalence of HPV in ...
متن کاملInvestigating the Prevalence of Human Papilloma Virus in Squamous Cell Carcinoma of the Larynx and Its Correlation with Disease Prognosis
Introduction: The human papilloma virus (HPV) can play a role in the development of head and neck squamous cell carcinoma (SCC). Our aim was to assess the prevalence of HPV DNA in SCC of the larynx. The impact of HPV infection on patient survival was also evaluated. Materials and Methods: This case-control study was performed in 44 patients with SCC of the larynx (case group), while the contro...
متن کاملRole of human papilloma virus infection and oral-genital contact in oral cancer ethiopathogenesis.
Head and neck squamous cell carcinoma and especially oropharyngeal squamous cell carcinoma is a very significant cause of morbidity and mortality. The majors risk factors of these tumors are tobacco smoking, chewing and alcohol consumption. But there is a group, non-drinking and non-smoking, patients with oropharyngeal squamous cell carcinoma. In these patients may be oral-genital contact and h...
متن کاملHuman papilloma virus infection in non-cancerous versus normal esophageal tissue samples by endoscopy
Abstract Background: Cancers are the second most common cause of non-accidental deaths in Iran, after cardiovascular mortality. Although most cases of esophageal squamous cell carcinoma (ESCC) in the USA and western populations have been attributed to high levels of exposure to tobacco and alcohol, but in Iranian populations the other risk factors especially infectious agents have been postula...
متن کامل