Anti-Müllerian Hormone Serum Concentrations of Women with Germline BRCA1 or 2 BRCA2 Mutations

نویسندگان

  • Kelly-Anne Phillips
  • Ian M. Collins
  • Roger L. Milne
  • Sue Anne McLachlan
  • Michael Friedlander
  • Martha Hickey
  • John L. Hopper
  • Richard Fisher
  • Gordon Kannemeyer
  • Sandra Picken
  • Charmaine D. Smith
چکیده

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منابع مشابه

Anti-Müllerian hormone serum concentrations of women with germline BRCA1 or BRCA2 mutations

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Objective(s): Breast cancer is the most common cancer in women. Every year, one million new cases are reported worldwide, representing 18% of the total number of cancer in women. Hereditary BRCA1 and BRCA2 mutations account for about 60% of inherited breast cancer and are the only known causes of hereditary breast cancer syndrome. The aim of this study was to determine the frequency of BRCA2 (e...

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Germline mutations in BRCA1, BRCA2 and TP53 genes have been identified as one of the most important disease-causing issues in young breast cancer patients worldwide. The specific defective biological processes that trigger germline mutation-associated and -negative tumors remain unclear. To delineate an initial portrait of Brazilian early-onset breast cancer, we performed an investigation combi...

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تاریخ انتشار 2017