Hidde Ploegh: Immunologist, journeyman

The God of Christianity and the G . O . D . of Immunology : Chance , Complexity , and God ’ s Action in Nature

ASA member Craig M. Story is an associate professor of biology at Gordon College in Wenham, Massachusetts. He received his BS in biology from Gordon in 1989, and his Ph.D. from Brandeis University. He was a post-doc at MIT and Harvard Medical School in the laboratory of immunologist Hidde L. Ploegh, who is now at the Whitehead Institute in Cambridge, MA. Craig enjoys fishing, reading, and talki...

Derlin-2 deficient mouse reveals an essential role for protein dislocation in chondrocytes

1. Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA. 2. Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA 3. Massachusetts Institute of Technology, Cambridge, MA 02139 4. Department of Molecular and Cellular Biology and Center for Brain Science, Harvard University, Cambridge, MA 02138, USA 5. Departm...

Just Passive Passengers The Peptide Cargo of Class I Molecules: Not

Lysosomal Cysteine and Aspartic Proteases

Supplemental Table S 1

Plasmids and cloning cDNA for human USP4 and USP8 was a gift from Hidde Ploegh and cDNA for USP39 was a gift from R. Medema. USP4CD (aa 296-954) and the D1 fragment (aa 296-490) of human USP4, USP39CD (aa 219-565) and USP8CD (aa 771-1118) were cloned using ligation independent cloning into pET-46 Ek/LIC vector (Novagen). The D2 fragment (aa 766-932) of USP4 was cloned into the pET-NKI b/3C (Lun...