Mechanism of the Propionyl Carboxylase Reaction

نویسنده

  • SEVERO OCHOA
چکیده

A study of the exchange reactions between adenosine triphosphate and either radioactive inorganic phosphate, or adenosine diphosphate (l), catalyzed by propionyl carboxylase, showed that inorganic phosphate was required for adenosine triphosphate-adenosine diphosphate exchange and, conversely, adenosine diphosphate was required for adenosine triphosphateinorganic phosphate exchange. A requirement for bicarbonate was also evident. These results suggested Reaction 1 as a single, partial step in the over-all Reaction 3.

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تاریخ انتشار 2003