Microevolution of Mycobacterium tuberculosis in a tuberculosis patient.
نویسندگان
چکیده
Five Mycobacterium tuberculosis isolates were obtained from three body sites from a Dutch patient. The isolates displayed a single genotype by 24-locus MIRU-VNTR typing (except for a single locus not amplified from one isolate) but were differentiated by small variations in IS6110 fingerprints, spoligotypes, 6 hypervariable MIRU-VNTR loci, and/or DiversiLab profiles, revealing patterns of microevolution in a clonal infection.
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ورودعنوان ژورنال:
- Journal of clinical microbiology
دوره 48 10 شماره
صفحات -
تاریخ انتشار 2010