Reduction of endotoxin levels in influenza virus vaccines by barium sulfate adsorption-elution.
نویسندگان
چکیده
The level of endotoxin in influenza virus vaccine lots was reduced 10- to 20-fold after barium sulfate adsorption-elution. The amount of viral antigen lost was negligible.
منابع مشابه
Purification of large quantities of influenza virus by density gradient centrifugation.
New zonal centrifuges can conveniently process as much as five orders of magnitude (10(5)) greater sample volumes than conventional swinging-bucket rotors. The continuous-sample-flow-with-banding versions may be used in series with ancillary purification procedures. Here we have studied the combined process: absorption and elution of influenza virus with barium sulfate followed by concentration...
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ورودعنوان ژورنال:
- Applied microbiology
دوره 30 2 شماره
صفحات -
تاریخ انتشار 1975