Article 3.indd

نویسندگان

  • Marna E. Sakalem
  • Giuseppina Negri
  • Ricardo Tabach
چکیده

The diversifi ed genus Passifl ora is well distributed all over Brazil, and many species have been long used as medicinal plants, mainly against anxiety disturbances. This effect has been attributed to its rich fl avonoid composition. Flavonoids’ main class, fl avonoid glycosides, has presented central action, particularly as sedativehypnotic, anxiolytic and analgesic. The objective of the present study was to make a phytochemical screening of fi ve little studied Passifl ora species, in order to evaluate their phenolic composition. For this aim, HPLC-DAD-ESI-MS/MS was used. After the preparation of the hydroalcoholic extracts, each species was evaluated by direct injection electrospray ionization (ESI) and tandem mass spectrometry. Although belonging to the same genus, the composition of each species presented particularities; this justifi es the importance of studies aiming for the phenolic composition of different Passifl ora species. Flavones C-glycosides were detected in all extracts, and are found as the main constituents in P. vitifolia, P. coccinea, P. bahiensis and P. sidifolia. In this last one, fl avone-6,8-di-C-glycoside, apigenin-6-C-rhamnosyl-8-C-arabinoside are present in high content. Cyclopassifl osides were found in high content together with cyanogenic glycosides in P. quadrangularis, while in P. coccinea, besides fl avones-Cglycosides were also found procyanidins.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Synthesis and Reactions of 3-Unsubstituted 2-Isoxazolines

Pohjakallio_176x250.indd 3 4.3.2011 10.34 Abstract_Pohjakallio_176x250.indd 3 4.3.2011 10.34Pohjakallio_176x250.indd 3 4.3.2011 10.34 2-Isoksatsoliinit ovat heterosyklisiä yhdisteitä, joita voidaan käyttää monipuolisesti synteettisinä välivaiheina erilaisten hyödyllisten rakenneyksiköiden valmistamisessa. 2-Isoksatsoliinien hyödyllisyys on pitkään perustunut niiden helppoon synteesiin erityises...

متن کامل

Intranasal drug delivery in neuropsychiatry: focus on intranasal ketamine for refractory depression.

Intranasal drug delivery (INDD) systems offer a route to the brain that bypasses problems related to gastrointestinal absorption, first-pass metabolism, and the blood-brain barrier; onset of therapeutic action is rapid, and the inconvenience and discomfort of parenteral administration are avoided. INDD has found several applications in neuropsychiatry, such as to treat migraine, acute and chron...

متن کامل

Vet July 2013.indd

Oral canine malignant melanoma is a spontaneous, locally aggressive, and highly metastatic tumour. A full clinical staging is required prior to plan a proper treatment, which will combine an aggressive local treatment with systemic therapy (chemotherapy or immunotherapy). This article aims at guiding the practitioners in the first steps of diagnosis and staging and also at providing data regard...

متن کامل

Building an integrated neurodegenerative disease database at an academic health center.

BACKGROUND It is becoming increasingly important to study common and distinct etiologies, clinical and pathological features, and mechanisms related to neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and frontotemporal lobar degeneration. These comparative studies rely on powerful database tools to quickly generate data sets that match...

متن کامل

58-61-Fea GuiBy_11-06.indd

102 10 1 10-1 10-2 10-3 10-4 10-5 10-6 10-7 10-8 10-9 10-10 10-11 10-12 10-13 printers who were diligent in communicating with one another, the materials and processes involved in UV curing have become much better understood. This article will try to explain some of the mysteries and myths of UV curing typically confronted by printers who are new to the technology. These mysteries and myths are...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012