Does Integron-Coded Protein Structure Depicts Simplicifolious and Non Simplicifolious Relationship?

The study evaluated the association between evolutionary relationship and the protein structure of class 1 integron-coded proteins of Citrobacter freundii and Serratia marcenscens. The prediction of the secondary structure of the class 1 integron coded protein was carried out using SOPMA tool. Results of the NCBI queries revealed significant identity with class 1 integron of the studied organisms. The nucleotide sequence alignment depicted lesser numbers of conserved regions with varying degree of transitions, transversions, insertions and deletions. The isolates contained comparatively higher random coils and alpha helix than both extended strands and the beta turn which were present in less percentages ranging from 17.46-22.42% and 11.48-8.56% respectively. In conclusion, this study confirmed a very strong association between the protein structure and the simplificifolius relationship observed in this study. [B.T. Thomas, Q.C. Ogueri, J. Ladan and O.A. Omolade. Does Integron Coded Protein structure Depicts Simplicifolious and Non Simplicifolious Relationship? Biomedicine and Nursing 2016;2(1):1-3]. ISSN 23798211 (print); ISSN 2379-8203 (online). http://www.nbmedicine.org. 1. doi:10.7537/marsbnj020116.01