Analysis of the Transfer RNA Population of Mouse Mammary Glands Infected with a Latent Mammary Tumor Virus1
نویسنده
چکیده
(9, 12, 13) decreases the NaCI concentration necessary to elute them from MAK and reverse phase chromatography Type 2 columns. In contrast, hypermethylation increases the NaCI concentration required to elute these tRNA's. Therefore, we have compared the tRNA's of MTV-cannier C3H mice in the pneneoplastic state, C3Hf mice lacking MTV, and another strain, C57BL/6, lacking MTV and shown to be resistant to carcinogenesis (18). This was done in order to determine whether an isoaccepting tRNA is associ ated with the latent virus on whether a transcriptional chem ical modification of a host tRNA is induced by MTV.
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