IVF pregnancies: neonatal outcomes after the new Italian law on assisted reproduction technology (law 40/2004).
نویسندگان
چکیده
OBJECTIVE To compare maternal and neonatal outcome of pregnancies achieved by assisted reproduction technique (ART) according to the guidelines of the newly established Italian ART law 40/2004, with that of naturally conceived. DESIGN Three hundred and sixty-four ART pregnancies and 304 naturally conceived pregnancies were analyzed in terms of the incidence of obstetric complications and perinatal outcome. Control group was enrolled prospectively after being matched for an extensive number of maternal characteristics. RESULTS Among singletons, ART pregnancies when compared to naturally conceived pregnancies showed a higher incidence of pregnancy loss (23.4% versus 10.5%) and a lower mean birth weight. A higher but not significant incidence of small for gestational age fetuses was observed in ART pregnancies, compared to those from normally conceived pregnancies (7.2% versus 2.7%). Moreover, the ART pregnancies showed a slightly, but nonetheless significantly shorter mean gestational age (38.6 versus 39.3 weeks) and more frequent preterm deliveries (11%) than the control group (2.7%). No difference was found in terms of other obstetric complications such as pregnancy-induced hypertension, gestational diabetes and placental abruption. Neonatal outcome was similar in both groups. CONCLUSION Although the obstetric outcome among singleton ART pregnancies was good, these patients should be considered obstetric risk cases. The different frequency of complications is not related to maternal age or parity and could be the consequence of infertility or the procedures by which these women conceived. The reasons are, however, unclear and further studies are necessary.
منابع مشابه
The 2004 Italian legislation regulating assisted reproduction technology: a multicentre survey on the results of IVF cycles.
BACKGROUND The new Italian law, passed in 2004, regulating assisted reproduction technology imposes that no more than three oocytes can be fertilized at one time and that all embryos obtained must be transferred simultaneously. Oocyte cryopreservation is allowed while embryo cryostorage is banned. The aim of this study was to evaluate the clinical impact of these limitations. METHODS Seven It...
متن کاملThe new Italian IVF legislation.
Last February, the Italian Parliament gave final approval to a new Law regulating assisted reproduction technology. The new legislation fell short of the expectations of infertile couples and of all specialists in the field. There are three problems with the new Italian law; they involve social issues, human rights and the application of technology. The present paper focuses on the fact that th...
متن کاملThe new Italian law on assisted reproduction technology (Law 40/2004)
The Italian parliament passed the law on assisted reproduction after a heated debate. The promulgation of this law (Law 40/2004) is the end point of a long and troubled journey that has seen many bills come and go, all of which have failed. The law consists of a whole set of regulations that will have a great impact on health and on society in general. The law is against many of the technical p...
متن کاملP-166: Obstetric and Neonatal Outcomes of Twin Pregnancies Conceived by Assisted Reproductive Techniques Compared with Natural Conceived Twins: A Prospective Follow-Up Study
Background: Comparison of obstetric and neonatal outcomes of twin pregnancies conceived by assisted reproduction technology (ART) with those of spontaneously conceived (SC). Materials and Methods: In this prospective cohort study, all dichorionic twin pregnancies following fresh IVF/ intra-cytoplasmic sperm injection (ICSI) or ICSI cycles (n=320) and (SC) (n=170) in nulliparous women in Royan I...
متن کاملThe effect of legislation on outcomes of assisted reproduction technology: lessons from the 2004 Italian law.
OBJECTIVE To evaluate the effect of the 2004 Italian regulations (insemination of <or=3 oocytes/cycle, transfer of all embryos, prohibition of embryo cryopreservation) on outcomes of assisted reproduction treatment (ART). DESIGN Case-control study. SETTING The Center of Reproductive Medicine, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy. PATIENT(S) Women undergoing ART for the firs...
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ورودعنوان ژورنال:
- Acta obstetricia et gynecologica Scandinavica
دوره 87 9 شماره
صفحات -
تاریخ انتشار 2005