Pharmacokinetics of esomeprazole following intravenous and oral administration in healthy dogs
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The full terms of the License are available at http://creativecommons.org/licenses/by/4.0/. The license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 2016 Cook et al. This work is published and licensed by Dove Medi l Press Limited. The full terms of this lic nse are ava lable at https://www.dovepress.com/terms. p p and incorporate the Creative Commons Attribution – Non Commercial (unp rted, v3.0) Licen e (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). Veterinary Medicine: Research and Reports 2016:7 123–131 Veterinary Medicine: Research and Reports Dovepress
منابع مشابه
Pharmacokinetics and Acid Suppressant Efficacy of Esomeprazole after Intravenous, Oral, and Subcutaneous Administration to Healthy Beagle Dogs
BACKGROUND Esomeprazole is an S-enantiomer of omeprazole that has favorable pharmacokinetics and efficacious acid suppressant properties in humans. However, the pharmacokinetics and effects on intragastric pH of esomeprazole in dogs have not been reported. OBJECTIVE To determine the pharmacokinetics of esomeprazole administered via various routes (PK study) and to investigate the effect of es...
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