Process for the synthesis of α, β-unsaturated esters
نویسندگان
چکیده
The present invention provides a process for the synthesis of an α,β-unsaturated ester from a mono-olefinester using Fe(CO).sub.5.
منابع مشابه
Microwave assisted Pd(OAc)2-catalyzed chemoselective reduction of aryl α,β-unsaturated esters with triethylsilane
< p>In this communication, we have reported that the Pd(OAc)2–Et3SiH-DMF system promotes the microwave-assisted chemoselective reduction of aryl α,β-unsaturated esters in good yields. The protocol affords a convenient reduction of aryl-conjugated double bonds even in presence of other functional groups like esters, phenols, and ethers.
متن کاملSynthesis of α, β-unsaturated γ-amino esters with unprecedented high (E)-stereoselectivity and their conformational analysis in peptides.
Mild, efficient and racemization-free synthesis of N-protected α, β-unsaturated γ-amino esters with unprecedented high E- stereoselectivity is described. This method is found to be compatible with Boc-, Fmoc- and other side chain protecting groups. The crystal conformations of the vinylogous γ-amino esters in monomers and in homo- and mixed dipeptides are studied. Further, the vinylogous homo-d...
متن کاملSynthesis of α,β-unsaturated γ-amino esters with a quaternary center by ruthenium-catalyzed codimerization of N-acetyl α-arylenamines and acrylates.
Ruthenium-catalyzed highly selective codimerization of N-acetyl α-arylenamines with ethyl acrylates is reported. This codimerization reaction provides a new efficient method for the synthesis of α,β-unsaturated γ-amino esters with a quaternary center.
متن کاملSynthesis and stereochemical analysis of β-nitromethane substituted γ-amino acids and peptides.
The high diastereoselectivity in the Michael addition of nitromethane to α,β-unsaturated γ-amino esters, crystal conformations of β-nitromethane substituted γ-amino acids and peptides are studied. Results suggest that the N-Boc protected amide NH, conformations of α,β-unsaturated γ-amino esters and alkyl side chains play a crucial role in dictating the high diastereoselectivity of nitromethane ...
متن کاملSynthesis of optically active dihydropyrans from asymmetric [4 + 2] cycloaddition of β,γ-unsaturated α-ketoesters with allenic esters.
β-Isocupreidine (β-ICD) catalyzed asymmetric [4 + 2] cycloaddition of β,γ-unsaturated α-ketoesters with allenic esters afforded ester-substituted functionalized dihydropyran derivatives in high yields along with high enantioselectivities under mild conditions.
متن کامل