Effects of Aquilaria crassna on Xanthine Oxidase Activity In Vitro and Hyperuricemic Mice
نویسنده
چکیده
Department Pharmacology, Faculty of Pharmacy, Mahidol University, Bangkok, 10400, 1Pharmaceutical Chemistry and Natural Products Research Unit, Faculty of Pharmacy, Mahasarakham University, Mahasarakham, 44150, 2Department of Thai Traditional Medicine, Faculty of Science and Technology, Bansomdejchaopraya Rajabhat University, Bangkok, 10600, Thailand, 3Department of Pharmacokinetics and Pharmacodynamics, School of Pharmacy, Showa University, Tokyo, 1428555, Japan
منابع مشابه
Traditional Uighur Medicine Karapxa decoction, inhibits liver xanthine oxidase and reduces serum uric acid concentrations in hyperuricemic mice and scavenges free radicals in vitro
BACKGROUND Karapxa decoction (KD) is a Traditional Uighur Medicine used for hepatitis, cholecystitis, gastralgia, oedema, gout and arthralgia. Because of its purported effect in gout, its effects were tested in hyperuricemic mice models induced by yeast extract paste or potassium oxonate, as well as its capacity to scavenge free radicals in vitro. METHODS Hyperuricemia was induced in mice by ...
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Xanthine oxidase plays crucial roles in the production of reactive oxygen species (ROS), and uric acid in blood which may lead to gout, one of the oldest known forms of arthritis amongst humans. Summer savory (Satureja hortensis L.) a medicinal/spice exhibits antioxidant activity, but unknown effects on xanthine oxidase activity. Here, for the first time, we examined the effects of S. hortensis...
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In Thailand, the leaves of Aquilaria crassna have been used traditionally for the treatments of various disorders, but without any scientific analysis. In this study, the antipyretic, analgesic, anti-inflammatory and anti-oxidative properties of A. crassna leaves extract were investigated at a wide dose range in rodents. Experimental animals were treated orally with an aqueous extract of Aquila...
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Antidiabetic effect of the water extract of Aquilaria crassna (A. crassna) leaves was recently claimed by some diabetic patients in Thailand, whereas its experimental evidence has not been published yet. The present study was therefore conducted to investigate pharmacological activities of the water extract of A. crassna leaves, focusing on its antioxidative and hypoglycemic effects in vitro an...
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Tabebuia species (Bignoniaceae) have long been used in folk medicine as anti-inflammatory, antirheumatic, antimicrobial, and antitumor. The aim of this study was to investigate if aqueous extract from the leaves (AEL) of Tabebuia roseoalba (Ridl.) Sandwith, Bignoniaceae, and its constituents could be useful to decrease serum uric acid levels and restrain the gout inflammatory process. HPLC anal...
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