Anti-Müllerian Hormone Is a Marker of Gonadotoxicity in Pre- and Postpubertal Girls Treated for Cancer
نویسندگان
چکیده
منابع مشابه
Anti-Müllerian hormone is a marker of gonadotoxicity in pre- and postpubertal girls treated for cancer: a prospective study.
CONTEXT Cytotoxic treatment may accelerate depletion of the primordial follicle pool, leading to impaired fertility and premature menopause. Assessment of ovarian damage in prepubertal girls is not currently possible, but Anti-Müllerian Hormone (AMH) is a useful marker of ovarian reserve in adults. OBJECTIVE The objective of the study was to prospectively evaluate AMH measurement in children ...
متن کاملPnm-5: Anti-Mullerian Hormone in The Assessment and follow up of Cancer in Young Females
Background The impact of cancer therapy on the reproductive potential of patients is increasingly recognized because survival rates of patients have clearly improved in recent years. The study stressed the use of AMH may allow better prediction of chemotherapy-related risk to further fertility. MaterialsAndMethods A narrative review was performed within articles published at PubMed, Elsevier, S...
متن کاملDecreased serum anti-Müllerian hormone levels in girls with newly diagnosed cancer
W. van Dorp1,2,*, M.M. van den Heuvel-Eibrink2, A.C.H. de Vries2, S.M.F. Pluijm2, J.A. Visser3, R. Pieters2, and J.S.E. Laven1 Division of Reproductive Medicine, Department of Obstetrics and Gynaecology, Erasmus MC-University Medical Centre Rotterdam’s– Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands Department of Paediatric Oncology/Haematology, Erasmus MC-Sophia Children’s Hospital, Dr....
متن کاملAnti-Müllerian hormone as a marker of ovarian reserve in girls before, during and after treatment for childhood cancer
Background: Although tremendous progress in survival after childhood cancer has been achieved with a five-year survival rate just over 80% in the industrialized world, this increase in survival rate is not without cost. Two-thirds of survivors experience a treatment related health condition and the most common late sequelae are the endocrineand reproductive disturbances. Women are born with a f...
متن کاملOocyte cryopreservation for fertility preservation in postpubertal female children at risk for premature ovarian failure due to accelerated follicle loss in Turner syndrome or cancer treatments.
OBJECTIVE To preliminarily study the feasibility of oocyte cryopreservation in postpubertal girls aged between 13 and 15 years who were at risk for premature ovarian failure due to the accelerated follicle loss associated with Turner syndrome or cancer treatments. DESIGN Retrospective cohort and review of literature. SETTING Academic fertility preservation unit. PARTICIPANTS Three girls d...
متن کامل