Expanding the dental phenotype of non syndromic orofacial clefting
نویسندگان
چکیده
The test of our progress is not whether we add more to the abundance of those who have much it is whether we provide enough for those who have little. ii ACKNOWLEDGMENTS I would like to express my thanks to Dr. Lina Moreno for giving me the opportunity to be involved in this exciting project. With her guidance, knowledge, and encouragement she has helped me succeed and nourished my interest in research. I would also like to thank Dr. Mary Marazita for her invaluable expertise, guidance, and encouragement; Judith Resick for her logistical and data entry support and for keeping my project on track; Meg Cooper for providing statistical analysis, guidance and help with interpretation of results; Dr. Alex Vieira for his guidance and encouragement, and Rebecca DeSensi for her data management and entry support. I would like to thank the department of Oral Pathology, Radiology, and Medicine and the department of Orthodontics for providing office support and specifically to Dr. Michael Finkelstein for his encouragement and unwavering support in my career and to Linda Keller for her logistical support. I could not have completed this project without the support, love and encouragement from my wife, Erin and my two children Isaac and Elijah.
منابع مشابه
Van der Woude syndrome- a syndromic form of orofacial clefting
Van der Woude Syndrome is the most common form of syndromic orofacial clefting, accounting for 2% of all cases, and has the phenotype that most closely resembles the more common non-syndromic forms. The syndrome has an autosomal dominant hereditary pattern with variable expressivity and a high degree of penetrance with cardinal clinical features of lip pits with a cleft lip, cleft palate, or bo...
متن کاملReduction in non syndromic oral clefts following mandatory flour fortification with folic acid in Northern Iran
Background: Several studies have examined the effects of folic acid fortification on the occurrence of orofacial clefts. This study was carried out to evaluate the impact of flour fortification with folic acid on oral clefts in Northern Iran. Methods : In this hospital based study from March 2006 to September 2009, we screened the total number of live births at all hospitals in Golestan pro...
متن کاملReduction in non syndromic oral clefts following mandatory flour fortification with folic acid in Northern Iran
UNLABELLED Background Several studies have examined the effects of folic acid fortification on the occurrence of orofacial clefts. This study was carried out to evaluate the impact of flour fortification with folic acid on oral clefts in Northern Iran. METHODS In this hospital based study from March 2006 to September 2009, we screened the total number of live births at all hospitals in Golest...
متن کاملParental cigarette smoking, transforming growth factor-alpha gene variant and the risk of orofacial cleft in Iranian infants
Objective(s):We investigated the influence of genetic variation of the transforming growth-factor alpha (TGFA) locus on the relationship between smoking and oral clefts. Materials and methods:In this study 105 Iranian infants with non-syndromic cleft lip/palate and 218 controls with non-cleft birth defects were examined to test for associations among maternal exposures, genetic markers, and ora...
متن کاملReminiscencing the Genetics of Orofacial Clefting
Address for Correspondence: Dr. Subhra Mandal, M.B.B.S. , M.D. (Anatomy), Associate Professor, Dept. of Anatomy, Medical College Kolkata, West Bengal, India. Mobile. No: +919477458100 E-Mail: [email protected] *1 Associate Professor, Dept. of Anatomy, Medical College Kolkata, West Bengal, India. 2 Post Graduate Resident in DNB ( PMR), S.N.P. Hospital, Kolkata, West Bengal, India. 3 Additi...
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