Failure of oocyte maturation: possible mechanisms for oocyte maturation arrest.
نویسندگان
چکیده
For human IVF, the patient's ovaries are hormonally stimulated to ensure the collection of fully matured oocytes that are at the metaphase II stage. Only these oocytes can be successfully fertilized either when mixed with sperm or after ICSI. Nevertheless, in some cases immature or maturing oocytes are recovered from follicles. Surprisingly, sometimes these oocytes do not complete maturation when cultured in vitro, for unknown reasons. In this article we discuss some possible mechanisms that may be responsible for those atypical arrests.
منابع مشابه
OOCYTE MATURATION DEFECT Oocyte Maturation Failure, Oocyte Defect Syndrome, Bad Eggs Syndrome, Meiotic Arrest, Oocyte Arrest, Maturation Arrest Of Human Oocytes
Oocyte maturation arrest is a complex problem not clearly understood; only few cases showing a complete oocyte maturation failure has been reported previously, still the exact incidence remains unknown. Failure to resume meiosis (a specialized type of cell division that reduces the chromosome number by half) in vivo may arise at one of the following three levels: absent or incomplete luteinizin...
متن کاملOOCYTE MATURATION DEFECT Oocyte Maturation Failure, Oocyte Defect Syndrome, Bad Eggs Syndrome, Meiotic Arrest, Oocyte Arrest, Maturation Arrest Of Human Oocytes
Oocyte maturation arrest is a complex problem not clearly understood; only few cases showing a complete oocyte maturation failure has been reported previously, still the exact incidence remains unknown. Failure to resume meiosis (a specialized type of cell division that reduces the chromosome number by half) in vivo may arise at one of the following three levels: absent or incomplete luteinizin...
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ورودعنوان ژورنال:
- Human reproduction
دوره 18 11 شماره
صفحات -
تاریخ انتشار 2003