Allelic variation of bile salt hydrolase genes in Lactobacillus salivarius does not determine bile 1 resistance levels
نویسندگان
چکیده
Allelic variation of bile salt hydrolase genes in Lactobacillus salivarius does not determine bile 1 resistance levels 2 3 Fang Fang , Yin Li , Mario Bumann, Emma J. Raftis, Patrick G. Casey , Jakki C. Cooney, 4 Martin A. Walsh, and Paul W. O’Toole * 5 6 Department of Microbiology , Alimentary Pharmabiotic Centre , University College Cork, 7 Ireland. 8 MRC France, BM14, c/o ESRF, 6 rue Jules Horowitz, B.P. 220, 38043 Grenoble, France 9 Department of Life Sciences, and Materials and Surface Science Institute, University of Limerick, 10 Ireland 11 12 13 * For correspondence. Email: [email protected]; Tel. (+353) 21 490 3997; Fax: (+353) 21 14 4903101. 15 16 Present address: Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, P. R. 17 China 18 19 Running title: Lactobacillus salivarius bile salt hydrolase and bile resistance 20
منابع مشابه
Allelic variation of bile salt hydrolase genes in Lactobacillus salivarius does not determine bile resistance levels.
Commensal lactobacilli frequently produce bile salt hydrolase (Bsh) enzymes whose roles in intestinal survival are unclear. Twenty-six Lactobacillus salivarius strains from different sources all harbored a bsh1 allele on their respective megaplasmids. This allele was related to the plasmid-borne bsh1 gene of the probiotic strain UCC118. A second locus (bsh2) was found in the chromosomes of two ...
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