Asphalt Fume Characterization and Hazard Identification
نویسندگان
چکیده
RESEARCH SUMMARY: This research will be integral to development of sampling and analytical methods used to assess exposures to asphalt fumes and specific irritants and genotoxins. Laboratory research will be useful in designing better worker exposure protocols, identifying specific biomarkers to assess a worker's true exposure, and designing animal studies to evaluate physiological and toxicological effects associated with exposure.
منابع مشابه
Health Effects of Occupational Exposure to Asphalt
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متن کاملResearch on performance of environment-friendly fume-suppression asphalt and optimization design for road
Based on the analysis of the mechanism and hazards of asphalt fume, by adding two fume suppressant Mg(OH)2 and Al(OH)3 and two viscosity reducers Sasobit and ROADBIT-BPL, the paper optimized the mixture ratio for road use, and prepared the environment-friendly fume-suppression asphalt, and then conducted the performance tests to identify the optimum dosage. The results show that: the fume amoun...
متن کاملInhalation exposure of rats to asphalt fumes generated at paving temperatures alters pulmonary xenobiotic metabolism pathways without lung injury.
Asphalt fumes are complex mixtures of various organic compounds, including polycyclic aromatic hydrocarbons (PAHs). PAHs require bioactivation by the cytochrome P-450 monooxygenase system to exert toxic/carcinogenic effects. The present study was carried out to characterize the acute pulmonary inflammatory responses and the alterations of pulmonary xenobiotic pathways in rats exposed to asphalt...
متن کاملExposure to asphalt or bitumen fume and renal disease.
Exposure to asphalt or bitumen fume and renal disease EDITOR,—The correspondence from Dittmer and Armitage 1 provides further support for a causal association between exposure to various hydrocarbons and the development of renal disease. Since 1912, some case reports, 2–4 case-control studies, 5 and cross sectional 6 studies together with animal experiments 7 8 have provided compelling evidence...
متن کاملStatistical modelling of the determinants of historical exposure to bitumen and polycyclic aromatic hydrocarbons among paving workers.
INTRODUCTION An industrial hygiene database has been constructed for the exposure assessment in a study of cancer risk among asphalt workers. AIM To create models of bitumen and polycyclic aromatic hydrocarbons (PAH) exposure intensity among paving workers. METHODS Individual exposure measurements from pavers (N = 1581) were collected from 8 countries. Correlation patterns between exposure ...
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