Growth Hormone Deficiency in Autoimmune Pituitary Disorders
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چکیده
GH deficiency (GHD) can manifest in childhood as growth failure, delayed bone age and slow growth velocity, while in adults the picture is more complex and is characterised by negative effects on body composition, cardiovascular functions and poor quality of life. Life expectancy is reduced in adult patients with GHD as a consequence of cardiovascular and cerebrovascular events. Most, if not all, of the abnormalities improve or normalise with GH replacement. Side effects are minor and can be minimised by individualising dosage requirements.
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