Summary of symposium on transfer RNA and transfer RNA modification in differentiation and neoplasia.
نویسنده
چکیده
isomorphous replacements, for clarification and possible decision among the several structures proposed. tRNA has long been known to be rich in minor base modifications (6, 20), of which the most common is methylation, and this occurs on all 4 major bases. Data presented at this symposium by Stulberg and Shugart (72) support the logical inference that these base modifications change the tertiary structure of the tRNA's and modulate its
منابع مشابه
RNA secondary structure and qRT-PCR analyses pertained to expressed anti-CD25 CAR in NK-92 cell line
Background and Objectives: Tumor-infiltrating regulatory T (TI-Treg) cells perform the significant function in cancer immune escape. In this study, the third generation CAR construct was designed against human CD25 antigen, the significant cell surface biomarker of TI-Tregs. Methods: Initially, the construct of anti-CD25 CAR was designed. Using RNAfold web server, the RNA secondary structure wa...
متن کاملO-18: Epigenetic Modification of Cloned Embryo Development; State of ART
Background: At the outset of the somatic cell nuclear transfer (SCNT) process, the chromatin structure of the somatic cell which governs its state of differentiation undergoes dramatic changes, called reprogramming, and is compelled back to the embryonic stage. However, the overall epigenetic makeup of the resultant cloned embryos has been acknowledged far different from the fertilized embryos....
متن کاملP 64: Micro-Rna Disorder and Multiple Sclerosis
Noncoding ribonucleic acids micro-RNA is involved in the regulation of gene expression have major roles in the post-transcriptional level. A micro-RNA alone several causes down regulation of mRNA transcript of the target. Thus, small changes in the expression of a micro RNA may lead to significant changes in gene expression are different. Micro- RNA as key regulators of immune cell lineage diff...
متن کاملFunctional modification of 16S ribosomal RNA by kethoxal.
Kethoxal reacts with 30S ribosomal subunits to give totally inactive particles, as measured by in vitro protein synthesis. It is postulated that functional modification occurs at the binding site for transfer RNA since (a) loss of specific binding of transfer RNA, but not binding of messenger RNA, is simultaneous with loss of protein synthesis, and (b) loss of activity is inhibited by bound tra...
متن کاملAbility to use the right transfer method (TDR) to increase the feasibility of urban services in Karaj A Case Study: District No.1 and No.2 of Karaj city
Introduction: Today, the method of distribution, provision and realization of urban services is one of the important necessities of urban life and urban development plans. However, the use of traditional methods of providing land for urban services has led to the fact that many lands allocated for public services have not been realized and have created problems for citizens and city managers, a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Cancer research
دوره 31 5 شماره
صفحات -
تاریخ انتشار 1971