Evaluation of retinal nerve fiber layer thickness parameters in myopic population using scanning laser polarimetry (GDxVCC).

نویسندگان

  • Tanuj Dada
  • A Aggarwal
  • S J Bali
  • A Sharma
  • B M Shah
  • D Angmo
  • A Panda
چکیده

INTRODUCTION Myopia presents a significant challenge to the ophthalmologist as myopic discs are often large, tilted, with deep cups and have a thinner neuroretinal rim all of which may mimic glaucomatous optic nerve head changes causing an error in diagnosis. OBJECTIVE To evaluate the retinal fiber layer (RNFL) thickness in low, moderate and high myopia using scanning laser polarimetry with variable corneal compensation (GDxVCC). SUBJECTS AND METHODS One hundred eyes of 100 emmetropes, 30 eyes of low myopes (0 to - 4 D spherical equivalent(SE), 45 eyes with moderate myopia (- 4 to - 8D SE), and 30 eyes with high myopia (- 8 to - 15D SE) were subjected to retinal nerve fiber layer assessment using the scanning laser polarimetry (GDxVCC) in all subjects using the standard protocol. Subjects with IOP > 21 mm Hg, optic nerve head or visual field changes suggestive of glaucoma were excluded from the study. The major outcome parameters were temporal-superior-nasal-inferiortemporal (TSNIT) average, the superior and inferior average and the nerve fibre indicator (NFI). RESULTS The TSNIT average (p = 0.009), superior (p = 0.001) and inferior average (p = 0.008) were significantly lower; the NFI was higher (P less than 0.001) in moderate myopes as compared to that in emmetropes. In high myopia the RNFL showed supranormal values; the TSNIT average, superior and inferior average was significantly higher(p less than 0.001) as compared to that in emmetropes. CONCLUSION The RNFL measurements on scanning laser polarimetry are affected by the myopic refractive error. Moderate myopes show a significant thinning of the RNFL. In high myopia due to peripapillary chorioretinal atrophy and contribution of scleral birefringence, the RNFL values are abnormally high. These findings need to be taken into account while assessing and monitoring glaucoma damage in moderate to high myopes on GDxVCC.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Correlation of Retinal Vessel Analysis and Nerve Fiber Layer Thickness in Normal Tension Glaucoma

Background: To investigate the retinal vessel diameter and its possible relationship with the retinal nerve fiber layer (RNFL) thickness in normal tension glaucoma (NTG). Methods: 86 NTG patients with detailed eye examination including retinal vessel analysis (DVA) and measurement of the RNFL thickness with scanning laser polarimetry (SLP; GDxVCC) were included in this retrospective study. The ...

متن کامل

Scanning laser polarimetry and retinal thickness analysis before and after laser in situ keratomileusis.

PURPOSE To evaluate changes in retinal nerve fiber layer (RNFL) thickness after laser in situ keratomileusis (LASIK) using a scanning laser polarimeter with fixed corneal compensation (GDx) and the retinal thickness analyzer (RTA). METHODS Thirty-eight eyes of 19 healthy subjects (10 female and 9 male; mean age 37.0-/+8.8 years) underwent GDx and RTA measurements before and after LASIK. All s...

متن کامل

Comparison of Retinal Nerve Fiber Layer Profile in Subjects with Myopia and Emmetropia Using Scanning Laser Polarimetry

Purpose: To compare retinal nerve fiber layer (RNFL) profile in subjects with myopia and emmetropia using GDx variable corneal compensator (VCC) Methods: Besides ophthalmologic standard examination (refraction, visual acuity and slit-lamp examination, applanation tonometry, and funduscopy), perimetry and scanning laser polarimetry (SLP) were performed. 171 healthy age-matched subjects with low ...

متن کامل

The evaluation of retinal nerve fiber layer in pigment dispersion syndrome and pigmentary glaucoma using scanning laser polarimetry.

PURPOSE To measure the retinal nerve fiber layer thickness in patients with pigment dispersion syndrome (PDS) using scanning laser polarimetry and to compare these measurements with those of normal subjects and patients with pigmentary glaucoma (PG). METHODS Age-, sex-, and refractive error-matched subjects--18 patients with PDS, 18 patients with PG, and 20 healthy subjects--were evaluated by...

متن کامل

[The influence of intraocular pressure reduction with medication on retinal nerve fiber layer thickness measurements obtained with scanning laser polarimetry in glaucomatous and hypertensive eyes].

PURPOSE To evaluate changes in retinal nerve fiber layer thickness as measured by scanning laser polarimetry (SLP) after the use of medication to reduce intraocular pressure (IOP) in glaucomatous or ocular hypertensive patients. METHODS The authors prospectively enrolled 37 eyes of 37 patients in whom IOP was reduced by more than 25% after the use of medication. The images were obtained befor...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH

دوره 5 1  شماره 

صفحات  -

تاریخ انتشار 2013