Difficulty Weaning Off Cardiopulmonary Bypass: Role of Diabetes-Associated Cardiomyopathy

Diabetes mellitus is a progressive systemic disease that adversely affects cardiovascular function. Diabetesassociated cardiovascular changes are a major cause of morbidity and mortality worldwide. Clinical trials indicate that diabetes accelerates and worsens the prognosis of coronary atherosclerosis, is associated with a 3-fold increase in the incidence of heart failure and that it is independently associated with worse heart failure prognosis [1]. The prognostic implications of thought of specific diabetes-induced structural, metabolic and functional cardiovascular changes triggered scientists to introduce the term (diabetic cardiomyopathy, DCM) as a separate clinical phenotype of myocardial dysfunction [2].