Detection of hemagglutinins in cultures of squirrel monkey intestinal trichomonads.

Experimental genital trichomoniasis in the squirrel monkey (Saimiri sciureus).

The squirrel monkey (Saimiri sciureus) has been proposed as a model for urogenital trichomoniasis in man, but has not been accepted as such because of the purported presence of naturally occurring vaginal trichomonads in this animal. The study published here shows that these are easily eradicated organisms of intestinal origin, which eliminates the potential confusion created by them. In additi...

Acquisition and retention of viruses by Trichomonas vaginalis.

Recently described occurrence of virus-like particles (VLP) in some strains of Trichomonas vaginalis suggests the possibility that the pathogenic significance of this organism may be broadened by its potential for viral transmission. Inasmuch as neither the source nor the host range of the VLP are known, any hazard which they may present for man cannot be estimated. A model has been established...

Growth of African Horse Sickness Virus in Monkey Kidney Cell Cultures

Pathogenic Trichomonas vaginalis cytotoxicity to cell culture monolayers.

Exposure of monolayer cultures of human urogenital and vaginal (HeLa), human epithelial (HEp-2), normal baboon testicular (NBT), and monkey kidney (Vero) cells to live pathogenic Trichomonas vaginalis resulted in extensive disruption of monolayers. Trypan blue was taken up by all host cells released from cell monolayers, which indicated irreversible damage of these cell types by trichomonads. T...

Direct microscopical examination of tube cultures for the detection of trichomonads.