Diaphragm pacing and motor neurone disease: lessons for all?
نویسنده
چکیده
Respiratory physicians and neurologists should be cognisant of the respiratory complications of motor neurone disease http://ow.ly/TIxe5.
منابع مشابه
Protocol for diaphragm pacing in patients with respiratory muscle weakness due to motor neurone disease (DiPALS): a randomised controlled trial
BACKGROUND Motor neurone disease (MND) is a devastating illness which leads to muscle weakness and death, usually within 2-3 years of symptom onset. Respiratory insufficiency is a common cause of morbidity, particularly in later stages of MND and respiratory complications are the leading cause of mortality in MND patients. Non Invasive Ventilation (NIV) is the current standard therapy to manage...
متن کاملDiaphragm pacing in ventilatory failure.
Diaphragm pacing, which entails electrical stimulation to the phrenic nerve, is an effective means of managing patients with ventilatory insufficiency and intact lowermotor-neurone innervation of the diaphragm. The pacing apparatus is used to pace the right and left hemidiaphragms alternately to avoid fatigue, which may damage the muscle irreversibly. Among the important benefits of pacing in q...
متن کاملSafety and efficacy of diaphragm pacing in patients with respiratory insufficiency due to amyotrophic lateral sclerosis (DiPALS): a multicentre, open-label, randomised controlled trial
BACKGROUND Non-invasive ventilation is part of the standard of care for treatment of respiratory failure in patients with amyotrophic lateral sclerosis (ALS). The NeuRx RA/4 Diaphragm Pacing System has received Humanitarian Device Exemption approval from the US Food and Drug Administration for treatment of respiratory failure in patients with ALS. We aimed to establish the safety and efficacy o...
متن کاملIssues and Opinions Diaphragm Pacing in Amyotrophic Lateral Sclerosis: a Literature Review
Amyotrophic lateral sclerosis (ALS) remains a rapidly progressive fatal degenerative disease of motor neurons for which there are few interventions to slow disease progression or improve quality of life. A diaphragm pacing system was approved by the U.S. Food and Drug Administration in September 2011 for ALS under a Humanitarian Device Exemption. News of this approval has been met with a combin...
متن کاملClinical advances in diaphragm pacing.
Diaphragmatic pacing is a valuable tool that can significantly benefit certain patients with respiratory insufficiency provided they have an intact phrenic nerve and a functional diaphragm. Careful patient selection is critical to successful long-term results. The main populations that derive benefit from pacing include those with congenital or acquired central hypoventilation syndrome and more...
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عنوان ژورنال:
دوره 1 شماره
صفحات -
تاریخ انتشار 2015