The Ultrastructure of a Reptilian Myoneural Junction

Ultrastructure of Reptilian Myoneural Junction

The description of motor end-plates by Doy~re (15) in 1840 initiated a series of light microscope investigations leading to the cytological concepts of the structure of the motor end-plate described in the papers of Ktihne (26), Tiegs (44), Couteaux (6-10), and Gutman and Young (22). The hundredfold or more higher resolution of the electron microscope (EM) clearly offers promise of distinct adv...

Action of Inhibitors at the Myoneural Junction

1. A study is presented of the actions of certain inhibitors on the frog rectus abdominis muscle stimulated by acetylcholine. 2. A type of analysis has been developed which provides a reliable criterion for judging whether an inhibitor is competing with acetylcholine for receptors at the myoneural junction or whether acting by a different mechanism. 3. The "curares" are shown to act by competit...

Familial risks for diseases of myoneural junction and muscle in siblings based on hospitalizations and deaths in sweden.

Diseases of the myoneural junction and muscle are disabling and some are life-threatening. Recent successes in the identification of the underlying genetic mechanisms have had profound implication for their diagnostics, treatment and classification. We define familial risks for siblings who were hospitalized for or deceased from diseases of the myoneural junction and muscle. A nationwide databa...

The physiology and pathophysiology of the myoneural junction.

Ultrastructure of Somatic Muscle Cells in Ascaris Lumbricoides

Somatic muscle cells of Ascaris lumbricoides consist of three differently specialized components referred to as the fiber, which contains the contractile apparatus (described previously), the belly, and the arm. The belly is shown to be a sac of glycogen, which is depleted during starvation of the animal. The arm extends to a nerve cord where it establishes a myoneural junction characterized by...