Internal architecture design and freeform fabrication of tissue replacement structures
نویسندگان
چکیده
Modeling, design and fabrication of tissue scaffolds with intricate architecture, porosity and pore size for desired tissue properties presents a challenge in tissue engineering. This paper will present the details of our development in the design and fabrication of the interior architecture of scaffolds using a novel design approach. The interior architecture design (IAD) approach seeks to generate layered scaffold freeform fabrication tool path without forming complicated 3D CAD scaffold models. This involves: applying the principle of layered manufacturing to determine the scaffold individual layered process planes and layered contours; defining the 2D characteristic patterns of the scaffold building blocks (unit cells) to form the Interior Scaffold Pattern; and the generating the process tool path for freeform fabrication of these scaffolds with the specified interior architecture. Feasibility studies applying the IAD algorithm to example models with multi-interior architecture and the generation of fabrication planning instructions will also be presented. q 2005 Elsevier Ltd. All rights reserved.
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ورودعنوان ژورنال:
- Computer-Aided Design
دوره 38 شماره
صفحات -
تاریخ انتشار 2006