Metal-free N-arylation of secondary amides at room temperature.
نویسندگان
چکیده
The arylation of secondary acyclic amides has been achieved with diaryliodonium salts under mild and metal-free conditions. The methodology has a wide scope, allows synthesis of tertiary amides with highly congested aryl moieties, and avoids the regioselectivity problems observed in reactions with (diacetoxyiodo)benzene.
منابع مشابه
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ورودعنوان ژورنال:
- Organic letters
دوره 17 11 شماره
صفحات -
تاریخ انتشار 2015