A rapid screen for molecules that form duplex to duplex crosslinks in DNA.
نویسندگان
چکیده
We describe a gold nanoparticle based assay that can rapidly determine the crosslinking of DNA duplexes by ligands. Such compounds have potential in targeting highly compacted DNA such as that found in the nucleosome.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 80 شماره
صفحات -
تاریخ انتشار 2013