Iron accumulation in deep gray matter of MS patients
نویسندگان
چکیده
Iris D Kilsdonk Mike P Wattjes Christian Langkammer Wolter L de Graaf Jette L Frederiksen Henrik BW Larsson Marios Yiannakas Claudia AM Wheeler-Kingshott Christian Enzinger Michael Khalil Mara A Rocca Till Sprenger Michael Amann Ludwig Kappos Massimo Filippi Alex Rovira Olga Ciccarelli Frederik Barkhof Franz Fazekas Multiple Sclerosis (2014) 20: 1692-1698 Determinants of iron accumulation in deep grey matter of multiple sclerosis patients 4.2
منابع مشابه
Quantitative assessment of iron accumulation in the deep gray matter of multiple sclerosis by magnetic field correlation imaging.
BACKGROUND AND PURPOSE Deposition of iron has been recognized recently as an important factor of pathophysiologic change including neurodegenerative processes in multiple sclerosis (MS). We propose that there is an excess accumulation of iron in the deep gray matter in patients with MS that can be measured with a newly developed quantitative MR technique--magnetic field correlation (MFC) imagin...
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BACKGROUND AND PURPOSE There is a well-established correlation between deep gray matter atrophy and cognitive dysfunction in MS. However, the cause of these signs of neurodegeneration is poorly understood. Iron accumulation in the deep gray matter is higher in patients with MS compared with age- and sex-matched healthy controls, and could contribute to disease progression. Our objective was to ...
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