Identification of a Kunjin/West Nile-like flavivirus in brains of patients with New York encephalitis.
نویسندگان
چکیده
Molecular analysis of brains from patients of the recent New York City encephalitis outbreak reveals the presence of a flavivirus not previously described in the Americas.
منابع مشابه
Genetic analysis of West Nile New York 1999 encephalitis virus.
Analysis of the genome of the flavivirus responsible for the 1999 New York City encephalitis epidemic cloned from human brain by reverse-transcription polymerase chain reaction Indicates its identity as a lineage I West Nile virus (WNV; WNV-NY1999) closely related to WNVs previously isolated In the Middle East.
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Dra. Maritza Pupo-Antúnez – Novia del Mediodía Km 6 1⁄2 La Lisa, Habana, Cuba. E-mail: [email protected] West Nile virus (WNV) is a flavivirus grouped in Japanese encephalitis virus serogroup due to serological antigenic characteristics. WNV is transmitted to humans through the bite of infected mosquitoes which acquire the virus after feeding on vertebrate amplifying hosts, mainly birds. WNV is ...
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Until recently, West Nile (WN) and Kunjin (KUN) viruses were classified as distinct types in the Flavivirus genus. However, genetic and antigenic studies on isolates of these two viruses indicate that the relationship between them is more complex. To better define this relationship, we performed sequence analyses on 32 isolates of KUN virus and 28 isolates of WN virus from different geographic ...
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West Nile virus, an Old World flavivirus related to St. Louis encephalitis virus, was first recorded in the New World during August 1999 in the borough of Queens, New York City. Through October 1999, 62 patients, 7 of whom died, had confirmed infections with the virus. Ornithophilic mosquitoes are the principal vectors of West Nile virus in the Old World, and birds of several species, chiefly m...
متن کاملWest Nile virus: a newly emergent epidemic disease.
536 West Nile (WN) virus is a mosquitoborne virus of the genus Flavivirus, family Flaviviridae. WN, Japanese encephalitis, St. Louis encephalitis, Murray Valley encepha-litis, and Kunjin viruses (along with other viruses) belong to the Japanese encephalitis serocomplex and are closely related to each other genetically and ecologically. The Japanese serocomplex of viruses has a near global distr...
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عنوان ژورنال:
- Lancet
دوره 354 9186 شماره
صفحات -
تاریخ انتشار 1999