A within-patient comparison of bethanidine, methyldopa and propranolol in the treatment of hypertension.
نویسندگان
چکیده
1. A within-patient comparison showed that bethanidine, methyldopa and propranolol produced similar control of the blood pressure. 2. Unlike bethanidine, propranolol did not produce postural and exercise hypotension; methyldopa was intermediate in effect. 3. Overall side effects were of a similar incidence though there were differences in incidence of particular side effects.
منابع مشابه
Within-patient Comparison
When a new agent is introduced into therapeutics it is important to obtain reliable comparison with existing drugs. Examination of the published reports on guanethidine, methyldopa, and bethanidine provides only an approximate estimate of their comparative merits. Most reports indicate that about 70% of patients achieve reasonable control of their blood pressure with each drug. However, the con...
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The effect of a low dose of methyldopa combined with (a) a non-selective and (b) a selective beta-adrenoceptor antagonist was studied in a double-blind crossover trial in 24 carefully selected patients with moderate hypertension (mean initial lying blood pressure 189/117 mm Hg). Each patient received methyldopa 750 mg/day, propranolol 240 mg/day, practolol 600 mg/day, methyldopa 750 mg/day comb...
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متن کاملThe ethnopharmacological review of medicinal plants in uses hypertension treatment in Iranian complementary medicine
Background & Aim: One of the most common diseases in the world, especially among Iranian people, is high blood pressure which can cause many cardiovascular disorders such as heart attack. The disease is often associated with other diseases such as diabetes and hyperlipidemia. Methyldopa and captopril are the most common drugs among several medications used to control blood pres...
متن کاملThe ethnopharmacological review of medicinal plants in uses hypertension treatment in Iranian complementary medicine
Background & Aim: One of the most common diseases in the world, especially among Iranian people, is high blood pressure which can cause many cardiovascular disorders such as heart attack. The disease is often associated with other diseases such as diabetes and hyperlipidemia. Methyldopa and captopril are the most common drugs among several medications used to control blood pres...
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ورودعنوان ژورنال:
- Clinical science and molecular medicine. Supplement
دوره 3 شماره
صفحات -
تاریخ انتشار 1976