Trimethyl 5-(2-chloro-4-fluorophenyl)-2-phenylpyrrolidine-2,3,4-tricarboxylate
نویسندگان
چکیده
The title compound, C(22)H(21)ClFNO(6), was synthesized by the 1,3-dipolar cyclo-addition reaction of dimethyl maleate, methyl 2-amino-2-phenyl-acetate and 2-chloro-4-fluoro-benzaldehyde. The pyrrolidine ring possesses an envelope conformation and the two benzene rings are oriented at a dihedral angle of 68.28 (7)°. Weak inter-molecular C-H⋯O hydrogen bonding is present in the crystal structure. One methyl group is disordered over two positions with a site-occupancy ratio of 0.651 (12):0.349 (12).
منابع مشابه
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عنوان ژورنال:
دوره 65 شماره
صفحات -
تاریخ انتشار 2009