Maxillary Ameloblastic Carcinoma in a Dog. In: Israel Journal of Veterinary Medicine (IJVM) Vol. 69 - N°2 - Jun. 2014

Aydogan, A. 98 INTRODUCTION Ameloblastic carcinoma (AC) is a malignant odontogenic epithelial tumor and combines the histologic features of the ameloblastoma. It is a rare tumor in humans and an extremely rare entity in domestic animals (1); the tumor has been reported in a horse and two dogs (2, 3, 4). It does not appear in the veterinary tumor classification and has malignant histopathological aspects such as cytologic atypia with or without metastasis (5, 6). Although ameloblastomas are well known and described in the literature, there is a little known about the ameloblastic carcinoma especially in domestic animals (7). In the present case, the tumor was classified according to the human tumor classification sytem based on histopathologic and immunohistochemical diagnosis. The aim of this report was to describe clinical, gross, microscopic, and immunohistochemical findings of a maxillary ameloblastic carcinoma in a dog. MATERIALS AND METHODS A 8-year-old, mix breed, male dog was presented to the Lara Antalya Veterinary Hospital for examination of a tumor mass on the right maxillary region of mouth (Figure 1). The mass had a nodular appearance and was painful. A radiographic examination of the chest did not show any evidence of metastasis. Oral radiographs did not clearly define the borders of the mass. The dog was in a good body condition and the hematological profile was normal. Under general anesthesia, the mass was excised with blunt dissection using cauterization. A 3 cm deep cavity appeared after dissection revealing the alveolar bone of the maxilla. Two of molar teeth were also extracted with the tumor. Severe bleeding of tumor area was observed after dissection which was stemmed using sponges. No adequate healthy gingiva and mucosa was available for suturing. Mouth disinfection was provided by using glycerine-iodine 3% solution (Ulkem Gliserin Iode, Ankara, Turkey) and broad spectrum antibiotics: Cefovecin Maxillary Ameloblastic Carcinoma in a Dog