Apolipoprotein E 4 influences on episodic recall and brain structures in aging pilots
نویسندگان
چکیده
Apolipoprotein E 4 influences on episodic recall and brain structures in aging pilots Maheen M. Adamson a,b,∗, Kelly M. Landy b, Susan Duong c,d, Sabrina Fox-Bosetti c,d, J. Wesson Ashford a,b, Greer M. Murphy b, Michael Weiner c,d, Joy L. Taylor a,b a Department of Veterans Affairs and Sierra-Pacific MIRECC, Palo Alto, CA, United States b Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, United States c Department of Veterans Affairs, San Francisco, CA, United States d University of California, San Francisco, CA, United States
منابع مشابه
The Visuospatial Episodic Memory in Persian-speaking Patients with Multiple Sclerosis
Background and purpose: Memory dysfunction is one the most common challenges of patients with Multiple Sclerosis (MS). Memory has a major role in daily life and influences social communication of individuals. The aim of this research was to investigate the function of nonverbal episodic memory in Persian speaker patients with MS. Materials and methods: In this cross-sectional study, 46 patient...
متن کاملUtilization of cognitive support in episodic free recall as a function of apolipoprotein E and vitamin B12 or folate among adults aged 75 years and older.
Apolipoprotein E (APOE), vitamin B12, and folate were examined in relation to free recall among 167 community-based older adults. Cognitive support at encoding and retrieval was also taken into account. Participants were classified as APOE e4 or non-epsilon4 allele carriers and as either low or normal vitamin B12 or folate status. A significant association was identified between low vitamin B12...
متن کاملCholesterol and triglycerides moderate the effect of apolipoprotein E on memory functioning in older adults.
We used data from the Betula Study to examine associations between total cholesterol, triglycerides, and apolipoprotein E on 10-year changes in cognitive performance. Tests assessing episodic memory (recall and recognition), semantic memory (knowledge and fluency), and visuospatial ability (block design) were administered to 524 nondemented adults (initial age of 55-80 years); multilevel modeli...
متن کاملAging and recollection in the accuracy of judgments of learning.
Dual-process theories propose that episodic memory performance reflects both recollection of prior details as well as more automatic influences of the past. The authors explored the idea that recollection mediates the accuracy of judgments of learning (JOLs) and may also help explain age differences in JOL accuracy. Young and older adults made immediate JOLs at study and then completed recognit...
متن کاملThe influence of APOE and TOMM40 polymorphisms on hippocampal volume and episodic memory in old age
Mitochondrial dysfunction is implicated in neurodegenerative disorders, such as Alzheimer's disease (AD). Translocase of outer mitochondrial membrane 40 (TOMM40) may be influential in this regard by influencing mitochondrial neurotoxicity. Little is known about the influence of the TOMM40 gene on hippocampal (HC) volume and episodic memory (EM), particularly in healthy older adults. Thus, we so...
متن کامل