A Versatile Sugar Transferase Makes the Cut
نویسنده
چکیده
The nutrient sensor O-GlcNAc transferase modifies proteins with the O-GlcNAc moiety. In this issue, Capotosti et al. (2011) reveal that O-GlcNAc transferase not only glycosylates the cell-cycle regulator host cell factor 1 but activates it through proteolytic cleavage, providing a surprising link between metabolism and epigenetic regulation of the cell cycle.
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ورودعنوان ژورنال:
- Cell
دوره 144 شماره
صفحات -
تاریخ انتشار 2011