Resistance to dual nucleoside reverse-transcriptase inhibitors in children infected with HIV clade A/E.

نویسندگان

  • Rangsima Lolekha
  • Sunee Sirivichayakul
  • Umaporn Siangphoe
  • Chitsanu Pancharoen
  • Suchada Kaewchana
  • Wichitra Apateerapong
  • Apicha Mahanontharit
  • Tawee Chotpitayasunondh
  • Kiat Ruxrungtham
  • Praphan Phanuphak
  • Jintanat Ananworanich
چکیده

The prevalence of nucleoside reverse-transcriptase inhibitor (NRTI) mutations was determined among 95 human immunodeficiency virus-infected Thai children who were treated with dual nucleoside reverse-transcriptase inhibitors. Almost all children had resistance to at least 1 NRTI, and approximately half of the children had resistance to multiple NRTIs. Cross-resistance to stavudine and azidothymidine was universal.

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عنوان ژورنال:
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

دوره 40 2  شماره 

صفحات  -

تاریخ انتشار 2005