Contrasting relationship between the Beijing genotype of Mycobacterium tuberculosis and MDR-TB in England versus Peru. http://ow.ly/qjxTG
نویسندگان
چکیده
Helen R. Stagg, Ted Cohen, Mercedes C. Becerra, Laura F. Anderson and Ibrahim Abubakar Research Dept of Infection and Population Health, University College London, and TB Section, Dept of Respiratory Diseases, Public Health England, London, UK. Division of Global Health Equity, Brigham and Women’s Hospital, Boston, MA, Dept of Epidemiology, Harvard School of Public Health, Boston, MA, and Dept of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
منابع مشابه
بررسی میزان وفور ژنوتیپ بیجینگ در سویههای مایکوباکتریوم توبرکلوزیس جدا شده از بیماران مسلولThe Frequency of Beijing Genotype of Mycobacterium Tuberculosis Isolated from Tuberculosis Patients
Background & Aim: Molecular epidemiology is the using of molecular techniques (e.g. Spoligotyping, RFLP VNTR) in order to study bacterial distribution in human populations. The aim of this study was to investigate the prevalence of all genotypes in M. tuberculosis strains typed by spoligotyping and to determine the associated risk factors in patients with different nationalities residing in...
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BACKGROUND Multidrug resistant tuberculosis (MDR-TB) is a major threat for global tuberculosis control. The W-Beijing Mycobacterium tuberculosis genotype has been associated with drug resistance. Elucidation of the mechanisms underlying this epidemiological finding may have an important role in the control of MDR-TB. The aim of this study was to evaluate the fitness of drug-susceptible and MDR ...
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BACKGROUND Drug resistant (DR) and multi-drug resistant (MDR) tuberculosis (TB) is increasing worldwide. In some parts of the world 10% or more of new TB cases are MDR. The Beijing genotype is a distinct genetic lineage of Mycobacterium tuberculosis, which is distributed worldwide, and has caused large outbreaks of MDR-TB. It has been proposed that certain lineages of M. tuberculosis, such as t...
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The Mycobacterium tuberculosis Beijing genotype has drawn attention because it is often strongly associated with multidrug-resistant tuberculosis (MDR-TB). A possible reason is that the Beijing strains may have an enhanced capacity to develop drug resistance. In this study, we used the Luria-Delbrück fluctuation test to investigate whether strains of Beijing and non-Beijing genotypes exhibit di...
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Although multidrug-resistant (MDR) tuberculosis (TB) is a major public health problem in Eastern Europe, the factors contributing to emergence, spread and containment of MDR-TB are not well defined. Here, we analysed the characteristics of drug-resistant TB in a cross-sectional study in Abkhazia (Georgia) between 2003 and 2005, where standard short-course chemotherapy is supplemented with indiv...
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