Proton MR spectroscopy in the diagnosis of early-stage subacute sclerosing panencephalitis.

نویسندگان

  • Mehmet Tekşam
  • Banu Cakir
  • Ahmet Muhteşem Ağildere
چکیده

Subacute sclerosing panencephalitis (SSPE) is a progressive, fatal neurological disorder of childhood and early adolescence. In this report, we present brain magnetic resonance spectroscopy (MRS) and conventional magnetic resonance MR imaging findings of early-stage (stage II) SSPE in an 8-year-old child. MRS demonstrated increased myo-inositol/creatine and choline/creatine ratios, and a decreased N-acetyl aspartate/creatine ratio. Conventional MR imaging demonstrated nonspecific, patchy T2 hyperintensities in the periventricular white matter and a nonspecific focus of T2 hyperintensity in the right frontal subcortical white matter. The MRS findings suggested active inflammation and demyelination as is seen in early-stage SSPE.

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منابع مشابه

Early- and late-state subacute sclerosing panencephalitis: chemical shift imaging and single-voxel MR spectroscopy.

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عنوان ژورنال:
  • Diagnostic and interventional radiology

دوره 12 2  شماره 

صفحات  -

تاریخ انتشار 2006